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Published clinical learning
Clinical update
Subclinical Coronary Atherosclerosis and Myocardial Infarction Risk: Evidence From a Danish CT Cohort
A Danish population cohort found less subclinical coronary atherosclerosis in women, while obstructive disease on CT was associated with higher myocardial infarction risk in both women and men.
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Mavacamten in Obstructive HCM: A US FDA Regulatory Reference From 2022
An FDA reference note on the 2022 US approval of mavacamten for symptomatic NYHA class II–III obstructive hypertrophic cardiomyopathy, including the monitoring and REMS requirements highlighted by the regulator.
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Finerenone in Cardio-Kidney-Metabolic Syndrome With Cancer History: FINE-HEART Insights
A large pooled post hoc analysis found that cancer history marked higher risk in cardio-kidney-metabolic syndrome, while finerenone benefits were consistent regardless of cancer history.
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Left Atrial Strain in ATTR-CM: What the HELIOS-B Secondary Analysis Adds
A secondary HELIOS-B analysis links impaired left atrial strain with worse outcomes in transthyretin amyloid cardiomyopathy and reports less worsening of strain with vutrisiran at 30 months.
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